Ergothioneine Extract Powder
Content: ≥99.5%
Country of Origin: China
Appearance: Off-white to white powder
Application: Cosmetics & Personal Care
Production Capacity: 2,000 kg/month
Shelf Life: Two years
Certifications: ISO9001, Kosher, Halal, FDA, IFEAT
Delivery Time: Delivery within one day from the warehouse
Delivery Terms: EXW, FOB, CIP, CIF, DAP
Transportation: Courier, Air, Ocean
Payment Terms: T/T preferred
Delivery: Ready stock, Prompt and Secure Shipment
Free Sample: Available
OEM/ODM: Available
MOQ: 1 kg
- Product Description
Ergothioneine Extract Manufacturer And Supplier
Xi'an Angel Biotechnology Co., Ltd. is an export-oriented enterprise specializing in the production of natural plant extracts, mainly developing and producing health care raw materials, natural sweeteners, flavors and fruit and vegetable extracts and other products. Ergothioneine Extract Powder is one of our products. The methods of extracting ergothioneine mainly include chemical synthesis, natural extraction, and biosynthesis. There are many extraction methods for ergothioneine, but each method has its limitations. Therefore, in practical applications, Angelbio chooses the most appropriate method according to specific needs and conditions to ensure the efficiency and purity of extraction.


Product Introduction
Ergothioneine Extract Powder is a high-purity cosmetic active known for its antioxidant properties. It can help support antioxidant-focused skincare formulations and is suitable for products designed to maintain healthy-looking skin and address daily environmental stress. With a purity of ≥99.5%, it can be incorporated into serums, creams, moisturizers, masks, and other personal care formulations.


Why Choose Us
Angelbio has advantages in independent facilities, R&D team, stable raw materials supply chain, strict quality control procedures and advacned testing methods. Please check below:
Over 18 years' synthetic and natural ingredients R&D experience and high credit among customers
1. Manufacturer and Supplier
- Two facilities in Shaanxi Province;
- Continuous production to ensure on-time delivery;
- Competitive price and trusted after-sales service
2. Technology Advantages
- Advanced testing equipment: HPLC, UV, GC
- Professional Team: 18 years R&D experience
- Testing items: pesticides, heavy metals, microbiology, solvents, solubility, etc.
3. Quality Assurance
- Strict testing and traceability procedures
- Complete certification including Kosher, Halal, ISO9001, REACH and FDA registration, IFEAT member etc.;
- Working with SGS, Eurofins, and other authorized laboratories.

Product Advantages
High-Purity Ergothioneine: With a purity of ≥99.5%, Ergothioneine Extract Powder is designed for applications requiring a high-purity antioxidant active.
Antioxidant Properties: Ergothioneine has been widely studied for its antioxidant activity and ability to interact with reactive oxygen species, making it suitable for antioxidant-focused skincare formulations.
Healthy-Aging Applications: Its antioxidant positioning makes Ergothioneine a suitable active for formulations targeting healthy-looking, smoother, and more resilient skin.
Formulation Versatility: Suitable for facial serums, creams, lotions, masks, eye-care products, and other personal care formulations.
Combination Potential: Ergothioneine can be formulated alongside complementary skincare ingredients such as hyaluronic acid, ceramides, niacinamide, vitamin C derivatives, and botanical antioxidants.
B2B Formulation Support: Available for bulk sourcing, customized formulations, OEM/ODM projects, and product development according to customer requirements.
Flow Chart
1. It is recommended that ergothioneine be added below 35°C during the final production step.
2. When ergothioneine is added, it cannot be combined with alkaline substances. It is recommended to add it together with a small amount of citric acid dissolved in water.

Product Specification
Product name | Ergothioneine Powder |
Test Item | Specification | Result | Method |
Physical and Chemical Analysis | |||
Appearance | Off-white to white powder | Conforms | Organoleptic |
Identification | HPLC retention time corresponds to RS | Conforms | USP <621> |
Optical rotation (c = 1, H2O) | ≥ (+) 122° | +133.1° | USP <781> |
Purity | ≥ 99.5% | 100.0% | USP <621> |
Loss on Drying (dried at 105°C for 3 hours) | ≤ 0.5% | 0.1% | USP <731> |
Assay (dry basis) | ≥ 99.0% | 99.9% | USP <621> |
Heavy Metals | < 10 ppm | < 10 ppm | ChP 2020, Part 4, 0821 |
Lead (Pb) | < 1.0 ppm | < 1.0 ppm | USP <233> |
Mercury (Hg) | < 0.1 ppm | < 0.1 ppm | USP <233> |
Arsenic (As) | < 1.0 ppm | < 1.0 ppm | USP <233> |
Cadmium (Cd) | < 0.3 ppm | < 0.3 ppm | USP <233> |
Microbiological Analysis | |||
Total plate count | ≤ 500 cfu/g | < 10 cfu/g | ISO 4833-1 |
Yeast and Mold | ≤ 100 cfu/g | < 10 cfu/g | ISO 21527 |
Salmonella | Negative in 10 g | Negative | ISO 6579-1 |
E. coli | Negative in 10 g | Negative | ISO 16649-3 |
S. aureus | Negative in 10 g | Negative | USP <62> |
Others | |||
Storage Condition | Stored in tightly sealed container, at a temperature not exceeding 30 °C, away from moisture and direct sunlight. Use it as soon as possible after unpacking. | ||
Packing | Double PE bags in an aluminum foil bag. | ||
Shelf Life | 24 months from manufacturing date. | ||
Research Highlights
1. Antioxidant Protection
Ergothioneine is recognized for its antioxidant activity and its ability to help neutralize reactive oxygen species.

2. Antioxidant Activity
Research indicates that ergothioneine can contribute to antioxidant defense by interacting with reactive oxygen species.

3. Skin Conditioning Support
Ergothioneine can be incorporated into formulations designed to support skin condition and maintain a healthy-looking skin barrier.

4. Cellular Antioxidant Support
Ergothioneine is efficiently handled by cells through the OCTN1 transporter and has been investigated for its antioxidant and cytoprotective properties.

5. Research on Ergothioneine and Skin Hydration
A randomized, double-blind, placebo-controlled study of an ergothioneine-rich mushroom preparation reported improvements in selected skin moisture and texture parameters following oral intake. These findings provide supportive evidence for the broader relationship between ergothioneine and skin condition, but should not be interpreted as clinical proof of topical Ergothioneine Extract Powder efficacy.

Our Certification
1. We own Kosher, Halal, ISO9001 certificates and are registered under EU REACH and FDA requirements, as well as being an IFEAT member.
2. Long-terms cooperation with SGS, Eurofines and other authorized institutes for quality assurance.

Our Exhibition
Angelbio regularly participates in industry exhibitions and professional events to connect with ingredient buyers, formulators, brands, and distribution partners.
These events provide opportunities to present our cosmetic ingredients, discuss formulation needs, and develop long-term B2B partnerships.
Meet us at upcoming industry events to discuss Ergothioneine Extract Powder, customized specifications, samples, and bulk supply.

Our Equipment
Professional Production & Testing
Angelbio operates professional production and quality-control facilities to support consistent Ergothioneine Extract Powder quality.
Our capabilities include HPLC, UV, and GC analysis, along with testing for purity, heavy metals, pesticides, residual solvents, and microbiological quality.
We support bulk supply, customized specifications, OEM/ODM projects, and ongoing B2B orders.

Technical Features
High Purity: ≥99.5% Ergothioneine.
Antioxidant Active: Suitable for antioxidant-focused skincare formulations.
Formulation Versatility: Suitable for creams, serums, masks, moisturizers, and personal care products.
- Quality Control: Supported by routine analytical and microbiological testing.
What we do in the Lab for quality assurance?

1. Physical test: appearance, odour, bulk density, particle size
2. Chemical test: purity, drying losses, ash
3. Pesticides residue test
4. Heavy metals test
5. Solvents residue test
6. Microbiological test
7. Nutrition labels testing
8. Other testing requested by customers
Product Application
Ergothioneine Extract Powder is suitable for cosmetic and personal care formulations focused on antioxidant protection, healthy-aging, skin conditioning, and hydration support.
Facial Serums: Suitable for antioxidant and healthy-aging formulations.
Anti-Aging & Healthy-Aging Creams: Can be combined with complementary skin-conditioning ingredients.
- Moisturizers: Suitable for formulations focused on maintaining skin hydration and a healthy-looking appearance.
- Facial Masks: Suitable for antioxidant-focused skincare concepts.
- Eye Care Products: Can be incorporated into formulations targeting the appearance of tired-looking skin.
- Personal Care Products: Suitable for a variety of premium skincare and personal care applications.
It can be combined with hyaluronic acid, ceramides, niacinamide, vitamin C derivatives, and botanical antioxidants for multifunctional skincare formulations.
EGT+
Formulation Guidance
The appropriate use level of Ergothioneine should be determined according to the final product type, formulation system, ingredient compatibility, and applicable cosmetic requirements.
Ergothioneine can be combined with complementary cosmetic actives to develop multifunctional skincare formulations.
Example Formulation Systems
- Antioxidant System: Ergothioneine + Vitamin C Derivatives + Vitamin E
- Hydration System: Ergothioneine + Hyaluronic Acid + Glycerin
- Barrier Care System: Ergothioneine + Ceramides + Niacinamide
- Healthy-Aging System: Ergothioneine + Niacinamide + Hyaluronic Acid + Antioxidants
For specific formulation requirements, contact our technical team for product specifications and sample support.

Packing & Delivery
Packaging Details: 25 kg/drum, 1 kg/foil bag, or as requested.
Delivery: Large orders are shipped by air or sea for cost efficiency, while samples are shipped by express.

How To Order
1. Send Your Requirements
Share your required specification, quantity, packaging, and application.
2. Get Product Information
Receive specifications, documentation, pricing, and sample options.
3. Evaluate the Sample
Request a sample for formulation or quality evaluation.
4. Confirm the Order
Confirm specifications, quantity, packaging, and delivery terms.
5. Production & Delivery
We arrange production, quality control, packing, and shipment according to the agreed requirements.
Need a Custom Specification?
Contact our team for bulk supply, OEM/ODM projects, customized specifications, and documentation support.
Send Requirements → Get a Quote → Test the Sample → Place Your Order

OEM Service
We offer customized production solutions to meet your specific needs, including:
Customizable packaging and labeling.
Tailored product formulations.
Flexible order quantities to accommodate diverse business sizes.
Rigorous quality assurance processes to ensure product excellence.
FAQ
1. What is our Ergothioneine Extract Powder derived from?
Our powder is primarily derived from mushrooms and select plant sources known for their high ergothioneine content.
2. Is this ingredient suitable for sensitive-skin formulations?
Ergothioneine can be considered for a wide range of skincare formulations. Final product suitability should be evaluated based on the complete formulation, concentration, and relevant safety testing.
3. What certifications do you offer for this product?
Our powder meets ISO and GMP standards and is backed by rigorous quality testing.
4. Can this product be tailored to specific formulations?
Absolutely! We provide OEM services to customize formulations, packaging, and labeling according to your needs.
Contact Us
Ready to enhance your products with the premium benefits of Ergothioneine Extract Powder? Contact us today for more information and personalized solutions:
Email: angel@angelbiology.com
WhatsApp: +1 522-925-2740
Website: https://www.angelbiology.com/













